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Terry Young, PhD, is an epidemiologist with a specialty in sleep disorders. Dr. Young’s research focus is on the natural history of sleep apnea and other sleep disorders. Of particular interest is the role of sleep apnea in cardiovascular and behavioral morbidity. This research is based on overnight in-laboratory sleep studies and other protocols conducted every four years on a large population-based cohort of men and women: the Wisconsin Sleep Cohort. Data from this unique cohort, developed by Dr. Young over 10 years ago, uncovered the high prevalence of unrecognized sleep apnea in middle-aged adults. Her studies to date shown unrecognized sleep apnea in the general population to be associated with elevated blood pressure, motor vehicle accidents and quality of life. Current work includes analyses of the longitudinal data being continuously collected to investigate changes in sleep apnea progression over time, the causal role of sleep apnea and other sleep disorders in health outcomes, and the development of sleep disorders in women over the midlife age span and menopausal transition. For this, women are studied by home polysomnography biannually. Dr. Young also collaborates with molecular geneticists who identified the first human sleep gene (Clock) in identifying sleep patterns that may be influenced by genetic factors. Dr. young teaches Epidemiologic Methodology, PM 798, offered in the Spring Semester. The course builds on the fundamentals of epidemiology (PM 797), and covers study design, sample construction, data collection methods and measurement issues, with an emphasis on bias reduction.
Affiliations/Associations:
Associate editor, Sleep
Editorial board, Sleep Medicine Reviews and Sleep Research Online
Divisional Head (epidemiology), World Health Organization; worldwide project of sleep disorders
Program Committee, American Academy of Sleep Medicine
Program Committee, American Thoracic Society
International Task Force, Sleep-Disordered Breathing Syndrome Definitions and Measurement Techniques in Clinical Research
University of Wisconsin, Faculty development and award committee
Department of Population Health Sciences, Steering Committee and Curriculum Committee for Population Health Program
Representative Publications:
Young, T., L. Finn and M. Palta
(2001). "Nocturnal nasal congestion as a risk factor for snoring: a
population-based study." Archives of Internal Medicine.
Young, T. and P. Peppard (2001). Epidemiology of obstructive sleep apnea.
Breathing Disorders in Sleep. E. Phillipson and McNichols. London, WB Saunders.
Peppard, P. E., T. Young, M. Palta
and J. Skatrud (2000). "Prospective study of the association between
sleep-disordered breathing and hypertension." New England Journal of Medicine
342(19): 1378-84.
Peppard, P. E., T. Young, M. Palta, J. Dempsey and J. Skatrud (2000).
"Longitudinal study of moderate weight change and sleep-disordered breathing."
JAMA 284(23): 3015-21.
Phillips, B., T. Young, L. Finn, K. Asher, W. A. Hening and C. Purvis (2000).
"Epidemiology of restless legs symptoms in adults." Archives of Internal
Medicine 160(14): 2137-41.
Young, T. and P. Peppard (2000).
"Sleep-disordered breathing and cardiovascular disease: epidemiologic evidence
for a relationship." Sleep 23 Suppl 4: S122-6.
Young, T. and P. Peppard (2000). Epidemiologic evidence for an association of
sleep-disordered breathing with hypertension and cardiovascular disease. Sleep
Apnea: Implications in Cardiovascular and Cerebrovascular Disease. T. D. Bradley
and J. S. Floras. New York, Marcel Dekker: 261-283.
Morrell, M. J., L. Finn, H. Kim, P.
E. Peppard, M. S. Badr and T. Young (2000). "Sleep fragmentation, awake blood
pressure, and sleep-disordered breathing in a population-based study." American
Journal of Respiratory & Critical Care Medicine 162(6): 2091-6.
Nieto, F. J., T. B. Young, B. K.
Lind, E. Shahar, J. M. Samet, S. Redline, R. B. D'Agostino, A. B. Newman, M. D.
Lebowitz and T. G. Pickering (2000). "Association of sleep-disordered breathing,
sleep apnea, and hypertension in a large community-based study. Sleep Heart
Health Study." JAMA 283(14): 1829-36.
Kushida, C. A., D. Nichols, R. Simon,
T. Young, M. Grauke, J. Britxmann, P. Hyde and W. C. Dement (2000).
"Symptom-based prevalence of sleep disorders in an adult primary care
population." Sleep and Breathing 4: 11-15.
AASM Task Force, W. Flemons, D.
Buysse, S. Redline, T. Young, K. Strohl and A. Pack (1999). "Sleep-related
breathing disorders in adults: recommendations for syndrome definitions and
measurement techniques in clinical research." Sleep 22: 667-689.
Mignot, E., T. Young, L. Lin and L.
Finn (1999). "Nocturnal sleep and daytime sleepiness in normal subjects with
HLA-DQB1*0602." Sleep 22(3): 347-52.
Wetter, D. W., M. C. Fiore, T. B.
Young, J. B. McClure, C. A. de Moor and T. B. Baker (1999). "Gender differences
in response to nicotine replacement therapy: objective and subjective indexes of
tobacco withdrawal." Experimental & Clinical Psychopharmacology 7(2): 135-44.
Zielinski, J., A. Zgierska, M.
Polakowska, L. Finn, P. Kurjata, W. KupSc and T. Young (1999). "Snoring and
excessive daytime somnolence among Polish middle-aged adults." European
Respiratory Journal 14(4): 946-50.
Finn L, Young T, Palta M, Fryback D. Sleep-disordered breathing and self-reported general health status in the Wisconsin Sleep Cohort Study. Sleep 21:587-592, 1998.
Mignot E, Young T, Lin L, Finn L, Palta M. Reduction of REM sleep latency associated with HLA-DQB!*0602 in normal adults. Lancet 351:727-728, 1998
Kim H, Young T, Mathews C, Palta M, et al. Association between neuropsychological deficits and sleep disordered breathing in the Sleep Cohort Study. Am J Respir Crit Care Med, 156:1813-1819, 1997.
Young T, Peppard P, Palta M, Hla K, Finn L, Morgan B, Skatrud J. Population-based study of sleep disordered breathing as a risk factor for hypertension. Arch Int Med 157:1746-1752, 1997.
Young T, Blustein J, Finn L, Palta M. Sleep-disordered breathing and motor vehicle accidents in a population-based cohort. Sleep 20:608-613, 1997.
Courses Taught:
PHS 375: Concepts and Methods in Population
Health Sciences
Contact Information:
Theresa B. Young, Ph.D.
Department of Population Health Sciences
University of Wisconsin Medical School
502 North Walnut Street, Room 126
Madison, Wisconsin 53726-2335 USA
Phone: (608) 263-5832
Fax: (608) 262-8235
Email: tbyoung@facstaff.wisc.edu
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