Leonelo Bautista MD, MPH, Dr. PH

Assistant Professor

Email: lebautista@wisc.edu

Biography:

My main research interests include the distribution of cardiovascular diseases and risk factors in developing countries, the etiology of coronary heart disease, and the role of chronic mild inflammation and endothelial function on the development of essential hypertension. I am the Principal Investigator of the Consortium of Latin American Studies on Obesity (LASO). The main goal of LASO is to understand the causes and consequence of obesity in Latin America. A major topic of my research is the link between mild chronic inflammation and the development and clinical course of essential hypertension. I am also conducting studies on the role of quality of life, depression and socioeconomic factors on non-adherence to pharmacologic treatment among patients with hypertension.

Affiliations/Associations:

• Adjunct Professor, Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, MD
• Editorial Board Member, The Open Obesity Journal
• Society for Epidemiologic Research
• American College of Epidemiology
• American Heart Association

Select Publications:

1. Herrera VM, Casas JP, Miranda JJ, Perel P, Pichardo R, González A, Sánchez JR, Ferreccio C, Aguilera X, Silva E, Oróstegui M, Gómez LF, Chirinos JA, Medina-Lezama J, Pérez CM, Suárez E, Ortiz AP, Rosero L, Schapochnik N, Ortiz Z, Ferrante D, Diaz M, Bautista LE, on behalf of the investigators of the Latin-American Consortium of Studies in Obesity (LASO). Interethnic differences in the accuracy of anthropometric indicators of obesity in screening for high risk of coronary heart disease. International Journal of Obesity advance online publication, 24 February 2009; doi:10.1038/ijo.2009.35

2. Bautista LE, Vargas CI, Oróstegui M, Gamarra G. Population Based Case-Control Study of Renin-Angiotensin System Gene Polymorphisms and Hypertension Among Hispanics. J Hypertens Res 2008, 31(3): 401-408.

3. Bautista LE. Predictors of Persistence with Antihypertensive Therapy: Results from the NHANES. Am J Hypertens 2008, 21: 183-188.

4. Herrera VM, Oróstegui M, Aguilera X, Ferreccio C, Silva E, Clavell E, Pichardo R, Gonzalez A, Casas JP, Lanas F, Avezum A, Bautista LE, Diaz R, Luna M, Islam S, Yusuf S. Risk factors for acute myocardial infarction in Latin America: the INTERHEART Latin American study. Circulation 2007, 115: 1067-1074.

5. Casas JP, Cavalleri GL, Bautista LE, Smeeth L, Humphries S, Hingorani A. Endothelial Nitric Oxide Synthase Gene Polymorphisms and Cardiovascular Disease: A HuGE Review. Am J Epidemiol 2006, 164(10): 921-935.

6. Bautista LE, Oróstegui M, Vera LM, Prada GE, Orozco LC, Herrán OE. Prevalence and impact of cardiovascular risk factors in Bucaramanga, Colombia: Results from the Countrywide Integrated Noncommunicable Disease Intervention Programme (CINDI/CARMEN) baseline survey. Eur J Cardiovasc Prev Rehabil 2006, 13(5): 769-775.

7. Casas JP, Shah T, Cooper J, Hawe E, McMahon AD, Gaffney D, Packard CJ, O’Reilly DS, Juhan-Vague I, Yudkin JS, Tremoli E, Margaglione M, Di Minno G, Hamsten A, Kooistra T, Stephens JW, Hurel SJ, Livingstone S, Colhoun HM, Miller GJ, Bautista LE, Meade T, Sattar N, Humphries SE, Hingorani AD. Insight into the nature of the CRP-coronary event association using Mendelian randomisation. Int J Epidemiol 2006, 35(4): 922-931.

8. Hatzigeorgiou C, Taylor AJ, Feuerstein IM, Bautista LE, O’Malley PG. Antioxidant vitamin intake and subclinical coronary atherosclerosis. Preventive Cardiology 2006, 9: 75-81.

9. Yusuf S, Hawken S, Ôunpuu S, Bautista LE, Franzosi MG, Commerford P, Lang CC, Rumboldt Z, Onen C, Lisheng L, Tanomsup S, Razak F, Sharma AM, Anand S, on behalf of the INTERHEART Study Investigators. Obesity and the risk of myocardial infarction: a case-control study in 27,000 subjects from 52 countries. Lancet 2005, 366: 1640-49.

10. Casas JP, Bautista LE, Smeeth L, Sharma P, Hingorani AD. Homocysteine and Stroke: “Mendelian randomization” provides further evidence for a causal link. Lancet 2005, 365: 224-32.

11. Bautista LE, Vera LM, Arenas IA, Gamarra G. Independent association between inflammatory markers (C-reactive protein, interleukin-6, and TNF-α) and essential hypertension. J Human Hypertens 2005, 19: 149-154.

12. Casas JP, Hingorani AD, Bautista LE, Sharma PJ. Meta-analysis of Genetic Studies in Ischaemic Stroke: 32 genes involving ~18,000 cases and ~58,000 controls. Arch Neurol 2004; 61: 1652-1662.

Contact Information:

Address:
610 Walnut Street
WARF 703
Madison, WI 53726

Phone: (608) 265-6176

Fax: (608) 263-2820

Email: lebautista@wisc.edu