Brad Astor, PhD, MPH

My primary area of research is chronic kidney disease and its interaction with cardiovascular disease.  I have a special interest in biomarkers of kidney function and the associations of these biomarkers with clinical outcomes, including incident chronic kidney disease, cardiovascular disease and mortality.  I have pursued research in these areas in the general population (e.g., Atherosclerosis Risk in Communites [ARIC] Study, Multi-Ethnic Study of Atherosclerosis [MESA]) as well as in clinical trials (African American Study of Kidney Disease and Hypertension [AASK]) and observational studies of dialysis patients (Choices for Healthy Outcomes in Caring for ESRD [CHOICE]).

 

 

Astor BC, Matsushita K, Gansevoort RT, et al. Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts. Kidney Int. 2011

 

Astor BC, Levey AS, Stevens LA, Van Lente F, Selvin E, Coresh J. Method of glomerular filtration rate estimation affects prediction of mortality risk. J Am Soc Nephrol 2009; 20:2214-22.

 

Bash LD, Selvin E, Steffes MW, Coresh J, Astor BC. Poor glycemic control in diabetes and the the risk of incident chronic kidney disease even in the absence of albuminuria and retinopathy: the Atherosclerosis Risk in Communities (ARIC) Study. Arch Intern Med 2008; 168:1-8.

 

Bash LD, Coresh J, Köttgen A, Parekh RS, Fulop T, Wang Y, Astor BC. Defining incident chronic kidney disease in the research setting: the ARIC Study. Am J Epidemiol. 2009; 170:414-24.

 

Astor BC, Arnett DK, Brown A, Coresh J. Association of kidney function and hemoglobin with left ventricular morphology among African Americans: the Atherosclerosis Risk in Communities (ARIC) Study. Am J Kidney Dis 2004; 43:836-845.

 

Astor BC, Coresh J, Heiss G, Pettitt D, Sarnak MJ. Kidney function and anemia as risk factors for coronary heart disease and mortality: the Atherosclerosis Risk in Communities (ARIC) Study. Am Heart J 2006; 151:492-500.

 

Astor BC, Hallan SI, Miller ER III, Yeung E, Coresh J. Glomerular filtration rate, albuminuria and risk of cardiovascular and all cause mortality in the US population. Am J Epidemiol 2008; 167:1226-34.

 

Astor BC, Yi S, Hiremath L, Corbin T, Pogue V, Wilkening B, Peterson B, Lewis J, Lash JP, Van Lente F, Gassman J, Wang X, Bakris G, Appel LJ, Contreras G. N-terminal prohormone brain natriuretic peptide (NT-proBNP) as a predictor of cardiovascular disease and mortality in African Americans with hypertensive kidney disease: the African American Study of Kidney Disease and Hypertension (AASK). Circulation 2008; 117:1685-92.

 

Astor BC, Bhavsar NA. Is There Something Better than the Best Marker of Kidney Function? J Am Soc Nephrol. 2011.

 

Astor BC, Köttgen A, Hwang SJ, Bhavsar N, Fox CS, Coresh J. Trefoil Factor 3 Predicts Incident Chronic Kidney Disease: A Case-Control Study Nested within the Atherosclerosis Risk in Communities (ARIC) Study. Am J Nephrol. 2011; 34:291-297.

 

 

Phone: (608) 262-0361
Fax: (608) 262-6743
Email: bcastor@medicine.wisc.edu